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Detective Alex Cross arrests renowned plastic surgeon Elijah Creem for sleeping with teenage girls. Now, his life ruined, Creem is out of jail, and he has made sure that no one will recognize him by giving himself a new face. A young woman is found hanging from a sixth floor window, and Alex is called to the scene. The victim recently gave birth, but the baby is nowhere to be found. Before Alex can begin searching for the missing newborn and killer, he is called to investigate a second crime. All of Washington, D.C. is in a panic, and when a third body is discovered, rumours of three serial killers send the city into an all out frenzy. Alex's investigations are going nowhere, and he is too focused on the cases to notice that someone has been watching him and will stop at nothing until he is dead.